Pagoclone Pellets 10mg
€2.88
Stand-alone Product Short Description:
Introducing Pagoclone Pellets 10mg, a meticulously prepared and high-purity research chemical precisely formed into individual pellets for consistent dosing in scientific investigations. Pagoclone is a novel cyclopyrrolone derivative, known for its activity as a partial agonist at the GABA-A receptor. This compound has been a subject of significant interest in neuropharmacology, particularly concerning its anxiolytic-like and anticonvulsant properties observed in various preclinical models. Each pellet contains 10mg of ≥ 99% pure Pagoclone, ensuring unparalleled accuracy and reproducibility for your experimental protocols. This product is specifically formulated for controlled in vitro and in vivo (non-human) studies exploring GABAergic modulation, receptor binding kinetics, neurochemical pathways, and analytical method development. It is not intended for human consumption or animal consumption.
- Physical Properties:
- Form: Compressed solid pellets
- Color: White to off-white
- Appearance: Uniform, smooth, solid cylindrical or spherical pellets
- Chemical Properties (of Pagoclone):
- Chemical Name (IUPAC): 2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-(5-methyl-2-oxohexyl)-1H-isoindol-1-one
- Synonyms: RP 59037, CI-1043, IP-456, RP-62955
- Molecular Formula: C₂₃H₂₂ClN₃O₂
- Molar Mass: 407.9 g/mol
- CAS Number: 133737-48-1 (Note: Other CAS numbers like 133737-32-3 may also be associated with isomers or specific enantiomers; verify with lot-specific documentation.)
- Solubility: Soluble in polar organic solvents like DMSO and slightly in methanol; insoluble in water. (for research purposes only).
- Stability: Stable when stored under cool, dry, dark conditions, protected from light, heat, and moisture.
Price is per pellet
Buy Pagoclone Pellets 10mg: Premium Research Chemical for GABA-A Receptor & Neuropharmacological Studies
Elevate your scientific endeavors with our precisely dosed Pagoclone Pellets 10mg. As a trusted supplier to the global scientific community, we understand that the integrity and reproducibility of your experiments hinge upon the unwavering purity and consistent dosing of your research materials. Our Pagoclone Pellets deliver ≥ 99% pure Pagoclone, meticulously formed into controlled 10mg pellets, specifically engineered to meet the rigorous demands of advanced laboratory investigations into the fascinating realm of non-benzodiazepine GABA-A receptor modulators and their complex interactions within the central nervous system.
We are not merely a vendor; we are a dedicated partner committed to supporting your pursuit of scientific breakthroughs. With an uncompromising dedication to stringent quality control, ultra-discreet global delivery, and unparalleled customer support, we stand as your definitive source for high-purity Pagoclone Pellets for research. Whether your work involves intricate studies into GABA-A receptor binding profiles, explorations of anxiolytic or anticonvulsant mechanisms, investigations into the pharmacokinetic and pharmacodynamic profiles of novel non-benzodiazepine hypnotics, the development of robust analytical methods for trace detection, or the precise characterization of structure-activity relationships, our pre-measured 10mg Pagoclone Pellets provide the foundational accuracy and purity essential for achieving precise, reproducible, and profoundly meaningful results. We possess an in-depth understanding of the complex logistics involved in international shipping and the paramount importance of confidentiality in sensitive research domains. Our shipping processes are therefore meticulously optimized for ultimate discretion and efficiency, guaranteeing that your invaluable research materials arrive securely and promptly at your laboratory, anywhere in the world.
Key Features & Benefits of Pagoclone Pellets 10mg
Our Pagoclone Pellets are distinguished by a set of core attributes that underscore our unwavering commitment to superior quality and complete customer satisfaction:
- Exceptional Purity: Guaranteed ≥ 99% pure Pagoclone raw material, rigorously verified through comprehensive, independent analytical testing. This extraordinary level of purity is absolutely critical for achieving reproducible experimental results, meticulously minimizing any potential confounding variables in your sophisticated research.
- Precise, Pre-measured Dosage: Each pellet contains a meticulously weighed 10mg of Pagoclone, offering unparalleled consistency and ease of use in your research protocols, eliminating the need for precise weighing of powder.
- Versatile Research Applications: These pellets are ideally suited for a wide spectrum of advanced in vitro and in vivo (non-human) research applications, particularly within the domains of neurochemistry, pharmacology, and analytical chemistry. Explore the unique properties of this compound with confidence in its quality.
- Discreet & Secure Shipping: We place the utmost priority on your privacy and the absolute security of your order. All shipments are packaged with exemplary discretion in plain, completely unmarked envelopes or boxes, with absolutely no indication of the contents, our company name, or any identifying marks on the exterior of the parcel.
- Fast Worldwide Delivery: Our highly streamlined global logistics network ensures rapid processing and expeditious dispatch of your order, facilitating prompt delivery to leading research institutions and laboratories across the globe, irrespective of your geographical location.
Product Specifications
To facilitate your meticulous research planning and protocol development, here are the detailed specifications for our Pagoclone Pellets 10mg:
- Product Name: Pagoclone Pellets 10mg
- Pellet Contents: High-Purity Pagoclone
- Chemical Name (IUPAC): 2-(7-chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-(5-methyl-2-oxohexyl)-1H-isoindol-1-one
- Synonyms: Pagoclone, RP 59037, CI-1043, IP-456, RP-62955
- Molecular Formula: C₂₃H₂₂ClN₃O₂
- Molecular Weight: 407.9 g/mol
- Appearance (Pellet): White to off-white, solid, uniform pellets.
- Purity (Pagoclone): ≥ 99% (as rigorously confirmed by multiple analytical methodologies)
- Pellet Dosage: 10 mg Pagoclone per pellet
- CAS Number: 133737-48-1 (Confirm with CoA for specific lot)
- Storage: Store in a cool, dark, and exceptionally dry place, away from direct sunlight, high temperatures, and moisture. Keep the container tightly sealed.
- Shelf Life: Stable for extended periods when stored under the precisely recommended conditions. Refer to the specific batch certificate of analysis or product packaging for precise expiry dates.
Applications & Usage
Pagoclone is a compound of significant scientific interest within various research disciplines, particularly within the realm of in vitro and in vivo (non-human) pharmacological and neurobiological investigations. Researchers utilize Pagoclone Pellets for research to investigate its pure chemical properties and its complex interactions within biological systems, especially concerning its effects as a partial agonist at the GABA-A receptor.
Typical research applications may include, but are not limited to:
- GABA-A Receptor Binding Studies: Investigating Pagoclone’s affinity and selectivity for different subunits of the GABA-A receptor in isolated cell lines or brain tissue, to understand its specific modulation profile.
- Neuropharmacological Investigations: Exploring its influence on neuronal excitability, neurochemical transmission, and behavioral responses (e.g., anxiolytic-like, sedative, anticonvulsant effects) in controlled in vitro or in vivo (non-human) models, aiming to elucidate the neurochemical pathways affected by non-benzodiazepine compounds.
- Pharmacokinetic and Pharmacodynamic (PK/PD) Profiling: Conducting studies to determine the absorption, distribution, metabolism, and excretion (ADME) of pure Pagoclone in various research models, as well as its dose-response relationships at the molecular and physiological levels.
- Analytical Chemistry Research: Developing and validating robust, sensitive, and specific analytical methods (e.g., LC-MS/MS, GC-MS) for the precise detection, identification, and quantification of Pagoclone and its metabolites in various biological and environmental matrices, crucial for forensic and toxicological studies of novel psychoactive substances (NPS) or potential pharmaceutical candidates.
- Structure-Activity Relationship (SAR) Exploration: Contributing to a broader scientific understanding of how Pagoclone’s specific chemical structure, a cyclopyrrolone, relates to its unique pharmacological profile compared to benzodiazepines.
- Metabolism Studies: Investigating the enzymatic pathways and metabolites involved in Pagoclone breakdown in various biological systems.
It is absolutely crucial to reiterate that Pagoclone Pellets 10mg are strictly for research and laboratory use only. Any research involving this compound must adhere rigorously to all relevant scientific and industry standards, ethical guidelines, and institutional review board protocols. The contents of these pellets are not intended for direct human ingestion or for use in animals outside of ethically reviewed research protocols.
Purity & Testing
The defining characteristic of our Pagoclone Pellets is the exceptional purity of the Pagoclone, consistently achieving an impressive ≥ 99%. This unparalleled level of purity is not merely a statement but a verifiable fact, meticulously substantiated by a suite of rigorous and comprehensive analytical testing procedures conducted by independent, ISO-certified, and accredited laboratories. Our unwavering commitment to quality assures that when you buy Pagoclone Pellets from us, you are acquiring a product completely free from significant impurities that could compromise the integrity and validity of your critical experimental work.
Our typical, multi-stage testing procedures for the raw material and final product include:
- High-Performance Liquid Chromatography (HPLC): This gold-standard technique is employed to precisely determine the exact purity of the Pagoclone and to meticulously identify and quantify any trace impurities.
- Nuclear Magnetic Resonance (NMR) Spectroscopy: Both proton (¹H) and carbon (¹³C) NMR spectroscopy are utilized to provide exquisitely detailed information about the molecular structure of Pagoclone, unequivocally confirming its identity and ensuring there are no unintended structural deviations.
- Mass Spectrometry (MS): This powerful analytical tool identifies the precise molecular weight of the compound and is highly effective in detecting even trace-level impurities by meticulously analyzing their mass-to-charge ratio.
- Fourier-Transform Infrared (FTIR) Spectroscopy: FTIR provides a unique “fingerprint” of the compound, identifying the functional groups present and further confirming its chemical structure and overall purity.
- Elemental Analysis (EA): This technique determines the elemental composition (C, H, Cl, N, O) of the sample, which is then compared against the theoretical composition of Pagoclone, providing an additional layer of purity verification.
- Residual Solvents Analysis (GC-MS): Ensures that no harmful residual solvents from the synthesis or purification process are present.
Furthermore, we conduct weight uniformity testing on the finished pellets to ensure each pellet consistently delivers the specified 10mg dosage, providing reliable and reproducible experimental conditions for your research. The stringent application of these advanced, multi-modal analytical techniques guarantees that our Pagoclone Pellets deliver the consistent, high-grade purity and precise dosing absolutely essential for reproducible research. This superior quality directly translates to robust and reliable experimental outcomes, empowering researchers to draw accurate and defensible conclusions, thereby accelerating their scientific discoveries without any concerns about unexpected variables introduced by lesser-quality reagents.
Safety & Handling Guidelines
Pagoclone Pellets 10mg are strictly for research purposes only and are not intended for human consumption, animal consumption, medical use, diagnostic procedures, or therapeutic applications of any kind whatsoever. Researchers are mandated to handle this chemical with the utmost care and to adhere to all stringent laboratory safety protocols.
- Always wear appropriate personal protective equipment (PPE), including, but not limited to, a laboratory coat, chemical splash goggles or safety glasses, and chemical-resistant gloves (e.g., nitrile, neoprene) when handling the product.
- Work exclusively in a well-ventilated area or, ideally, under a certified chemical fume hood to minimize any potential inhalation exposure to airborne particles from crushed pellets.
- Avoid any direct contact with skin, eyes, and clothing. In the event of accidental contact, rinse the affected area thoroughly with copious amounts of water for at least 15 minutes and seek immediate medical attention if irritation or symptoms persist.
- Store the product securely in its original, tightly sealed packaging, in a cool, dark, and very dry environment, far removed from incompatible materials, unauthorized personnel, and any direct sources of sunlight or heat.
- Dispose of the product and any contaminated materials strictly according to all applicable local, regional, and national regulations for hazardous chemical waste.
- Always consult the comprehensive Safety Data Sheet (SDS) for Pagoclone for detailed hazard information, safe handling procedures, first-aid measures, and emergency protocols before any use.
Global Shipping & Discreet Delivery
We recognize that the secure and confidential procurement of research chemicals is as critically important as their intrinsic purity. Our robust global shipping infrastructure is meticulously designed to provide unparalleled service to the international scientific community, with an unwavering commitment to your absolute privacy and the secure, timely delivery of your order. When you choose to buy Pagoclone Pellets online from us, you benefit from a meticulously planned and executed delivery process:
- Worldwide Reach: We offer expedited and highly reliable shipping services to virtually every country across the globe, ensuring that researchers on all continents have seamless access to our high-quality products.
- Discreet Packaging: All orders are meticulously shipped in completely plain, nondescript packaging. There are absolutely no company logos, product names, or any other identifying marks whatsoever on the exterior of the parcel that would, in any way, indicate its sensitive contents.
- Secure Contents: The pellets are contained within a sealed, durable container, which is then securely packed to prevent any damage or tampering during transit.
- No Chemical Names on Parcel: For maximum security and unparalleled privacy, the shipping labels will never contain the precise chemical name of the product. Instead, generic descriptions (e.g., “scientific sample,” “laboratory material”) or non-descriptive codes are utilized to comply with international customs regulations without compromising your anonymity or the confidential nature of your purchase.
- Reliable Tracking: The vast majority of our international orders are dispatched with comprehensive tracking information, allowing you to closely monitor your shipment’s progress from the moment of dispatch right through to successful delivery, providing complete peace of mind.
- Efficient Logistics: Our strategic partnerships with leading global couriers and freight forwarders ensure that your order is processed with exceptional speed and efficiency, minimizing transit times and getting your invaluable research materials to your laboratory as swiftly as humanly possible.
We take immense pride in our ability to consistently offer truly stealth packaging that unequivocally prioritizes your confidentiality, establishing us as the preferred and trusted choice for research chemicals where discretion is of paramount importance.
Why Choose Us?
Selecting the right supplier for your critical research chemicals is a monumental decision that directly influences the validity, efficiency, and safety of your scientific endeavors. Here’s why scientists and research institutions across the globe implicitly trust us as their premier source for Pagoclone Pellets 10mg:
- Uncompromising Purity: Our steadfast commitment to consistently deliver 99%+ product purity, meticulously verified by extensive third-party testing, ensures reliable, reproducible, and impactful research outcomes.
- Precisely Dosed Pellets: Our 10mg pellets offer unparalleled convenience and accuracy for your research, ensuring consistent amounts of Pagoclone for your experimental designs.
- Dedicated Customer Support: Our team of highly knowledgeable, professional, and responsive customer support specialists is readily available to assist you with any inquiries, ranging from detailed product specifications to precise order tracking, ensuring a flawlessly seamless and positive purchasing experience.
- Fast & Reliable Shipping: We prioritize exceptionally rapid order processing and dispatch, synergistically coupled with highly efficient and robust global shipping services, to guarantee that your invaluable research materials reach your facility promptly, wherever you are situated in the world.
- Ultimate Stealth Packaging: We possess a profound understanding of the critical importance of discretion. Our packaging is meticulously engineered to be utterly plain, entirely unmarked, and securely contained, with no discernible identifying information, thereby guaranteeing absolute and complete confidentiality for your research needs.
- Trusted Global Reputation: Years of dedicated, ethical, and consistent service to the global scientific community have unequivocally cemented our reputation as a highly reliable, transparent, and trusted supplier of the highest quality research chemicals.
- Competitive Pricing: We are committed to offering premium quality products at highly competitive price points, thereby providing exceptional value for your critical research budget without ever compromising on our stringent purity standards or our superior service.
- Secure Payment Options: We provide a diverse range of robust and secure payment methods to ensure that all your transactions are processed safely, efficiently, and with the utmost protection of your financial information.
When you choose to buy Pagoclone Pellets from us, you are not merely acquiring a chemical compound; you are making a strategic investment in a partnership that unequivocally supports your ambitious scientific objectives with integrity, unwavering reliability, and unparalleled service.
Legal & Safety Disclaimer
Pagoclone Pellets 10mg are sold strictly and exclusively for legitimate scientific research and bona fide laboratory use only. The contents of these pellets are NOT FOR HUMAN CONSUMPTION, ANIMAL CONSUMPTION, MEDICAL USE, DIAGNOSTIC PROCEDURES, OR THERAPEUTIC PURPOSES OF ANY KIND WHATSOEVER.
- Research Use Only: This product is intended solely for in vitro and in vivo (non-human) research applications to be conducted exclusively by qualified, experienced, and competent professionals operating within strictly controlled laboratory environments. The pellets are designed for ease of handling and precise measurement of the Pagoclone for inclusion in experimental protocols, not for ingestion or administration to humans or animals.
- Age Restriction: By proceeding with the purchase of this product, the buyer explicitly confirms and warrants that they are at least eighteen (18) years of age.
- Legal Compliance (United States): The buyer assumes complete and absolute responsibility for comprehensively understanding and meticulously complying with all applicable local, state, and federal laws, statutes, and regulations pertaining to the purchase, possession, and use of this specific research chemical. Pagoclone is a non-benzodiazepine GABA-A receptor partial agonist. While not federally scheduled by name in the United States, its pharmacological activity means it could be covered by analogue acts if intended for human consumption or if determined to have a substantially similar chemical structure or pharmacological effect to a controlled substance. It is the buyer’s sole and unequivocal responsibility to verify and ensure that the product is entirely legal to import, possess, and utilize for their specific research application in their jurisdiction. We shall not be held liable or responsible for any legal repercussions, penalties, or damages arising from the misuse, illegal possession, or unlawful distribution of this product.
- Risk Assumption: The buyer explicitly acknowledges and accepts the inherent risks unequivocally associated with the handling and experimentation of research chemicals, particularly those with potent pharmacological properties. The buyer further agrees to diligently undertake all necessary and appropriate precautions, including, but not limited to, the consistent use of proper personal protective equipment (PPE) and strict adherence to established standard laboratory safety procedures and best practices.
- No Medical Claims: No claims, express or implied, are made or intended regarding the medical, therapeutic, recreational, or any other non-research-related uses of this product. Any such use is strictly and absolutely prohibited and is entirely contrary to the explicitly stated and intended purpose of this product.
- Waiver of Liability: By completing the purchase, the buyer irrevocably agrees to release, indemnify, defend, and hold harmless the supplier from any and all claims, demands, liabilities, actions, causes of action, or damages (including reasonable legal fees) whatsoever, arising directly or indirectly from the proper use, misuse, or illegal possession of the product.
This disclaimer serves as a critical and unambiguous reminder of the specific, limited, and legally defined scope of the product’s intended use and the comprehensive legal responsibilities incumbent upon the purchaser.
FAQ Section
Here are some frequently asked questions about Pagoclone Pellets 10mg:
Q1: What are Pagoclone Pellets 10mg used for in research?
A1: Pagoclone Pellets 10mg are primarily used for advanced scientific research focusing on GABA-A receptor pharmacology, neuropharmacology, and the exploration of anxiolytic or hypnotic-like properties in in vitro and in vivo (non-human) laboratory settings. They are used to study its chemical properties, biological interactions, and for analytical method development. They are not for human or animal consumption or recreational use.
Q2: Is it legal to purchase Pagoclone Pellets for research in the United States?
A2: Pagoclone’s legal status in the U.S. is complex. While not specifically scheduled, its activity as a GABA-A receptor partial agonist means it could be covered by the Federal Analogue Act if intended for human consumption. OUR PRODUCT IS SOLELY INTENDED FOR LEGITIMATE LABORATORY RESEARCH PURPOSES, NOT FOR HUMAN OR ANIMAL USE. Researchers are responsible for ensuring their specific use complies with all applicable local, state, and federal laws.
Q3: How discreet is shipping for Pagoclone Pellets?
A3: We prioritize discretion. All Pagoclone Pellet orders are shipped in plain, unmarked packaging with no company logos, product names, or identifying marks on the exterior. Generic descriptions are used for customs purposes to ensure your privacy and the secure delivery of your research materials.
Q4: What is the purity of the Pagoclone in these pellets, and how is it tested?
A4: Our Pagoclone Pellets contain ≥ 99% pure Pagoclone. This high purity is verified through rigorous third-party analytical testing, including HPLC, NMR, MS, FTIR, and Elemental Analysis. We also test for residual solvents and perform weight uniformity tests on the pellets to ensure consistent dosing.
Q5: What are the recommended storage conditions for Pagoclone Pellets?
A5: To maintain the long-term stability and optimal purity of the Pagoclone, it is highly recommended to store the pellets in their original, tightly sealed container in a cool, dark, and exceptionally dry place, away from direct sunlight, high temperatures, and moisture. Proper storage conditions are crucial for preserving the chemical integrity and ensuring the long-term viability of the product for your research purposes.
