Buy 25B-NBOMe – USA & Europe

1. What is 25B-NBOMe?

25B-NBOMe, also called NBOMe-2C-B or Cimbi-36, is a synthetic psychedelic research chemical of the NBOMe series, derived from the 2C-B phenethylamine. It acts as a potent full agonist at the serotonin 5-HT2A receptor, used primarily as a research tool for serotonin receptor mapping, neuropharmacology, and behavioral neuroscience studies. It is not intended for human consumption and is supplied for laboratory research use only.

2. Chemical Composition & Structure of 25B-NBOMe

The chemical name is 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine, commonly encountered as the hydrochloride salt. Its molecular formula is C1818H2222BrNO33, reflecting a phenethylamine backbone substituted with bromine and methoxy groups, as well as the N-(2-methoxybenzyl) group typical of NBOMe compounds.

3. Research Applications of 25B-NBOMe

Used extensively in binding assays and neuroimaging studies, 25B-NBOMe helps characterize serotonergic system dynamics and receptor affinity profiles. It is valuable in preclinical research focusing on hallucinogenic receptor activation mechanisms and for developing receptor-specific probes.

4. Recommended Laboratory Handling & Safety Guidelines

Handle 25B-NBOMe with gloves, lab coat, and eye protection. Use a fume hood for powder manipulation and avoid inhalation or skin exposure. All procedures should follow strict chemical safety protocols.

5. Hazard Warnings & Risk Statements (GHS Classification If Applicable)

• H302: Harmful if swallowed

• H315: Causes skin irritation

• H319: Causes serious eye irritation

• H335: May cause respiratory irritation

• Signal word: WARNING
  The compound has high potency and toxicity at low doses; safe handling and training are essential.

6. Compatibility with Other Reagents or Substances

Compatible with organic solvents such as methanol, ethanol, and DMSO. Avoid reactive oxidizers, strong acids, and bases that may destabilize the compound.

7. Emergency Protocols for Accidental Exposure

• Skin/eye contact: Rinse with water for 15 minutes

• Inhalation: Move to fresh air; medical attention if symptoms occur

• Ingestion: Seek emergency medical treatment immediately.

8. Storage Stability & Shelf Life Monitoring

Store in airtight, light-protected containers at low temperatures (2–8°C or below). To ensure stability, avoid moisture and repeated freeze-thaw cycles. Under correct storage, 25B-NBOMe remains stable for several years.

9. Can Researchers Purchase 25B-NBOMe Without a License?

Yes, research institutions and qualified researchers may purchase 25B-NBOMe with the responsibility to verify the chemical’s legal status in their country.

10. Is It Legal to Order 25B-NBOMe Online in My Country?

25B-NBOMe is highly regulated or banned in many countries, including the USA and much of Europe, as a Schedule I or equivalent controlled substance. Confirm local regulations prior to ordering.

11. Is 25B-NBOMe Considered Safe for Laboratory Use?

Laboratory use is safe when following controlled chemical handling procedures. Misuse carries severe health risks due to its high potency and toxicological profile.

12. Special Considerations for Researchers with Medical Conditions

Individuals with cardiovascular, psychiatric, or neurological issues should avoid contact due to the compound’s potent psychoactive effects.

13. Allergen Exposure Risks When Handling 25B-NBOMe

Not a documented allergen but gloves and PPE are recommended to prevent sensitization.

14. Can 25B-NBOMe Be Used in Combination with Other Research Materials?

Should be combined only with compatible solvents and inert chemicals; avoid reactive agents.

15. Can Pregnant Researchers Handle 25B-NBOMe?

Pregnant, breastfeeding, or immunocompromised personnel should avoid exposure.

16. Proper Handling Protocols for Best Experimental Consistency

Use precision balance and pipettes, minimize light/air exposure, and document all batches carefully.

17. Optimizing Research Output with 25B-NBOMe

Use freshest solvents, control storage temperature, and avoid freeze-thaw cycles to maintain compound integrity.

18. Reported Results and Efficacy in Experimental Settings

25B-NBOMe is a highly selective 5-HT2A receptor agonist used in high-precision receptor binding and neuroimaging protocols.

19. Known Adverse Reactions or Lab Incidents

Severe toxic events have been documented with uncontrolled exposure, highlighting the importance of strict lab safety procedures.

20. What To Do in Case of Severe Exposure or Contamination

Initiate decontamination immediately and seek professional medical help; provide emergency responders with SDS and chemical info.

21. Can Alcohol-Based Solvents Be Used with 25B-NBOMe?

Ethanol and methanol are suitable solvents for solution preparation at research concentrations.

22. What If I Skip a Scheduled Measurement or Test Cycle?

Discard unused solutions, prepare fresh batches for repeated experiments to avoid artifacts.

23. Maximum Recommended Duration of Experimental Storage or Use

Solid forms stable for years refrigerated; solutions best used within 1–3 months.

24. Stability After Discontinuation of Testing

Degradation occurs if exposed to moisture, air, or light for prolonged periods; proper logging advised.

25. Is There Risk of Dependency or Sensitization?

No known risk of physical dependency in lab settings; safety protocols reduce sensitization hazard.

26. Long-Term Storage Recommendations for 25B-NBOMe

Store in opaque, airtight vials, refrigerate at 2–8 °C or below, use desiccants to minimize moisture.

27. Alternative Research Chemicals with Similar Properties

• 25I-NBOMe (iodo analog)

• 25C-NBOMe (chloro analog)

• 2C-B (parent phenethylamine)

• DOI (related psychedelic phenethylamine)