Buy Noribogaine Hydrochloride – USA & Europe

1. What is Noribogaine Hydrochloride?

Noribogaine hydrochloride is the hydrochloride salt form of noribogaine, the primary active metabolite of ibogaine, a psychoactive indole alkaloid derived from the Tabernanthe iboga plant. Noribogaine has pharmacological and therapeutic relevance due to its prolonged action and interaction with multiple neurotransmitter systems, offering antiaddictive, antidepressant, and neuroprotective effects. It is extensively studied in addiction research and neuropsychiatry.

2. Chemical Composition & Structure

Noribogaine hydrochloride has the molecular formula C1919H2525ClN22O with a molecular weight of approximately 332.87 g/mol. Structurally, it differs from ibogaine by the replacement of the methoxy group on the indole ring with a hydroxy group at the 12-position, belonging to monoterpenoid indole alkaloids. The molecule contains a fused pentacyclic ring system characteristic of the iboga alkaloids.

3. Research Applications of Noribogaine Hydrochloride

Used primarily in pharmacological and neurobiological research, noribogaine hydrochloride acts as a:

• Serotonin uptake inhibitor

• NMDA receptor antagonist

• Kappa-opioid receptor agonist with G-protein bias
  Studies use it to explore mechanisms underlying anti-addiction therapies, antidepressant effects, and neuroplasticity modulation.

4. Recommended Laboratory Handling & Safety Guidelines

Handle using PPE including gloves, lab coat, and safety glasses. Work under ventilated conditions or fume hoods to prevent inhalation or dermal contact. Ensure precise dosing and controlled storage.

5. Hazard Warnings & Risk Statements (GHS Classification If Applicable)

Noribogaine is a bioactive substance with potential CNS and cardiovascular effects. Researchers should follow strict safety and exposure control procedures to mitigate risks.

6. Compatibility with Other Reagents or Substances

Stable in common organic solvents such as ethanol and methanol. Avoid strong acids, bases, and oxidants.

7. Emergency Protocols for Accidental Exposure

• Skin or eye contact: Rinse immediately with water for 15 minutes.

• Inhalation: Move person to fresh air and seek medical treatment if symptoms appear.

• Ingestion: Medical emergency assistance is required.

8. Storage Stability & Shelf Life Monitoring

Store in airtight, light-resistant containers at refrigerated temperatures (2–8°C). Proper storage extends shelf life for years.

9. Can Researchers Purchase Noribogaine Hydrochloride Without a License?

Yes, for research use with user responsibility for compliance with governing laws.

10. Is It Legal to Order Noribogaine Hydrochloride Online in My Country?

It is controlled or regulated in many jurisdictions. Verify local regulations before ordering.

11. Is Noribogaine Hydrochloride Considered Safe for Laboratory Use?

Safe when handled under stringent chemical safety protocols and PPE use.

12. Special Considerations for Researchers with Medical Conditions

Avoid contact by individuals with cardiovascular or neurological vulnerabilities.

13. Allergen Exposure Risks When Handling Noribogaine Hydrochloride

No specific allergenic information, but standard PPE is recommended.

14. Can Noribogaine Hydrochloride Be Used in Combination with Other Research Materials?

Typically compatible with solvents and reagents used in neuropharmacological studies.

15. Can Pregnant Researchers Handle Noribogaine Hydrochloride?

Not recommended.

16. Proper Handling Protocols for Best Experimental Consistency

Use precise balances and minimize exposure to air and light. Document all batch information.

17. Optimizing Research Output with Noribogaine Hydrochloride

Maintain solvent purity and consistent storage temperatures. Use fresh aliquots for experiments.

18. Reported Results and Efficacy in Experimental Settings

Noribogaine exhibits extended brain penetration and prolonged receptor modulation, contributing to its antiaddictive pharmacology and antidepressant effects in models.

19. Known Adverse Reactions or Lab Incidents

Risks primarily involve CNS depression and cardiovascular impacts; laboratory exposure risks controlled with PPE.

20. What To Do in Case of Severe Exposure or Contamination

Perform immediate decontamination and seek medical advice promptly.

21. Can Alcohol-Based Solvents Be Used with Noribogaine Hydrochloride?

Yes, ethanol and methanol are suitable solvents.

22. What If I Skip a Scheduled Measurement or Test Cycle?

Discard unstable samples, prepare fresh solutions for accuracy.

23. Maximum Recommended Duration of Experimental Storage or Use

Stable for extensive periods under optimal refrigerated storage.

24. Stability After Discontinuation of Testing

Potential degradation with prolonged exposure to light or oxygen; recommended protected storage.

25. Is There Risk of Dependency or Sensitization?

Not documented in research exposure; PPE advised to minimize risks.

26. Long-Term Storage Recommendations for Noribogaine Hydrochloride

Store refrigerated in airtight, opaque containers with desiccants.

27. Alternative Research Chemicals with Similar Properties

• Ibogaine HCl isolate

• Iboga PTA isolate

• Voacangine