MET Fumarate
$47.69
Stand-alone Product Short Description:
MET Fumarate (Monomethyl Fumarate) A premium-grade research reagent for advanced scientific and pharmacological studies.
Physical and Chemical Properties:
Appearance: White to off-white crystalline powder Molecular Formula: C₅H₆O₄ Molecular Weight: 130.10 g/mol Solubility: Highly soluble in water; soluble in acetone, ethanol, DMSO Purity: ≥98% (HPLC verified) Storage: -20°C, airtight container
Not for human consumption.
Price is per 0.5gram
Buy MET Fumarate (Monomethyl Fumarate): Premium Research Reagent
Elevate the precision and impact of your scientific investigations with our meticulously prepared MET Fumarate (Monomethyl Fumarate – MMF). As a leading supplier to research institutions and laboratories worldwide, we understand that the integrity and reproducibility of your experiments depend on the unwavering purity and consistent quality of your research materials. Our Monomethyl Fumarate delivers an exceptional purity of ≥98% of the active compound, rigorously verified through comprehensive analytical testing, ensuring it meets the exacting standards required for advanced pharmacological, biochemical, and immunological studies.
Monomethyl Fumarate (MMF) is the primary active metabolite of Dimethyl Fumarate (DMF), an FDA-approved medication used for the treatment of relapsing forms of multiple sclerosis (MS) and psoriasis. MMF is a dicarboxylic acid monoester known for its potent immunomodulatory, anti-inflammatory, and antioxidant properties. Its mechanism of action involves the activation of the Nrf2 (Nuclear factor erythroid 2-related factor 2) pathway, a key cellular defense against oxidative stress, and acting as an agonist for the G protein-coupled receptor 109A (GPR109A). This makes MMF an invaluable tool for exploring pathways related to cellular protection, inflammation, and neurodegenerative processes in controlled research environments. The pure powder form offers maximum flexibility for precise dosing and custom solution preparation in laboratory settings.
We are your dedicated partner in scientific discovery. With an unwavering commitment to stringent quality control, ultra-discreet global delivery, and unparalleled customer support, we stand as your definitive source for high-purity MET Fumarate for research. Whether your work involves intricate studies into its effects on immune cell function, explorations of its neuroprotective potential, investigations into its precise molecular targets, or the development of robust analytical methods for detection in biological matrices, our Monomethyl Fumarate provides the foundational accuracy and consistency essential for achieving precise, reproducible, and profoundly meaningful results. We possess an in-depth understanding of the complex logistics involved in international shipping and the paramount importance of confidentiality in sensitive research domains. Our shipping processes are therefore meticulously optimized for ultimate discretion and efficiency, guaranteeing that your invaluable research materials arrive securely and promptly at your laboratory, anywhere in the world.
Key Features & Benefits of MET Fumarate (Monomethyl Fumarate)
Our MET Fumarate is distinguished by a set of core attributes that underscore our unwavering commitment to superior quality and complete customer satisfaction:
- Exceptional Purity: Guaranteed ≥98% pure Monomethyl Fumarate content, rigorously verified through comprehensive, independent analytical testing (HPLC, NMR, MS). This high level of purity minimizes confounding variables in your sophisticated research.
- Well-Characterized Compound: A metabolite of an approved drug, making it highly relevant for understanding therapeutic mechanisms, drug metabolism, and disease pathways.
- Flexible Dosing: The pure powder form allows researchers to precisely measure and prepare custom solutions or dosages according to their specific experimental protocols.
- Potent Immunomodulator & Antioxidant for Research: Enables focused studies on a compound with documented effects on Nrf2 pathway activation, GPR109A agonism, and immunomodulatory properties in preclinical models.
- Broad Research Applications: This product is ideally suited for a wide spectrum of advanced in vitro and in vivo (non-human, under strict ethical protocols) research applications, particularly within the domains of immunology, neuroscience, pharmacology, and toxicology.
- Discreet & Secure Shipping: We place the utmost priority on your privacy and the absolute security of your order. All shipments are packaged with exemplary discretion in plain, completely unmarked envelopes or boxes, with absolutely no indication of the contents, our company name, or any identifying marks on the exterior of the parcel.
- Fast Worldwide Delivery: Our highly streamlined global logistics network ensures rapid processing and expeditious dispatch of your order, facilitating prompt delivery to leading research institutions and laboratories across the globe.
Product Specifications
To facilitate your meticulous research planning and protocol development, here are the detailed specifications for our MET Fumarate (Monomethyl Fumarate):
| Property | Value |
|---|---|
| Product Name | MET Fumarate (Monomethyl Fumarate) |
| Contents | High-Purity Monomethyl Fumarate |
| Formal Name | (2E)-4-methoxy-4-oxobut-2-enoic acid |
| Synonyms | MMF, Fumaric acid monomethyl ester, methyl hydrogen fumarate, Bafiertam |
| Molecular Formula | C₅H₆O₄ |
| Molecular Weight | 130.10 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (as rigorously confirmed by multiple analytical methodologies) |
| CAS Number | 2756-87-8 (also 44836-34-2) |
| Solubility | Highly soluble in water; soluble in acetone, ethanol, DMSO |
| Storage | -20°C (freezer) for long-term. Room temperature for short-term shipping. Dark, dry, airtight container. Protect from light and moisture. |
| Shelf Life | Refer to product label for specific expiry; stable for extended periods when stored under recommended conditions. |
Applications & Usage
MET Fumarate (Monomethyl Fumarate) offers an invaluable tool for researchers interested in the detailed pharmacology and biochemical pathways influenced by fumarate esters. Given its role as the active metabolite of an approved drug, it is particularly relevant for in vitro and, where ethically approved, in vivo (non-human) investigations into its mechanism of action, cellular interactions, immunomodulatory effects, and potential therapeutic applications. Researchers utilize MET Fumarate for research to investigate its pure chemical properties and its complex interactions within biological systems.
Typical research applications may include, but are not limited to:
- Immunology and Inflammation Research: Investigating its ability to modulate immune responses, reduce inflammation, and its potential in models of autoimmune diseases such as multiple sclerosis and psoriasis.
- Nrf2 Pathway Studies: Exploring its role in activating the Nrf2 antioxidant response pathway, which is crucial for cellular protection against oxidative stress and electrophilic insults.
- Neuroprotection Studies: Examining its potential neuroprotective effects in various neurological disease models, given its role in treating MS and its demonstrated effects in models of retinal disease and chronic pain.
- GPR109A Agonism: Studying its activity as an agonist for the GPR109A receptor and the downstream signaling pathways involved.
- Drug Metabolism and Pharmacokinetics: Using MMF as a reference standard in studies exploring the metabolism of Dimethyl Fumarate (DMF) and the pharmacokinetics of fumarate esters.
- Cellular Bioenergetics: Researching its impact on mitochondrial function and cellular energy metabolism.
- Analytical Chemistry: Developing and validating robust analytical methods for the detection and quantification of MMF in biological and environmental matrices.
It is absolutely crucial to reiterate that MET Fumarate is strictly for research and laboratory use only. Any research involving this compound must adhere rigorously to all relevant scientific and industry standards, ethical guidelines, and institutional review board protocols. The contents of this product are not intended for direct human ingestion, or any form of administration, nor for use in animals outside of ethically reviewed research protocols.
Purity & Testing
The defining characteristic of our MET Fumarate is the exceptional purity of the active compound, Monomethyl Fumarate, consistently achieving an impressive ≥98% purity. This unparalleled level of purity is not merely a statement but a verifiable fact, meticulously substantiated by a suite of rigorous and comprehensive analytical testing procedures conducted by independent, ISO-certified, and accredited laboratories. Our unwavering commitment to quality assures that when you buy MET Fumarate from us, you are acquiring a product completely free from significant impurities or contaminants that could compromise the integrity and validity of your critical experimental work.
Our typical, multi-stage testing procedures for the Monomethyl Fumarate API include:
- High-Performance Liquid Chromatography (HPLC): This gold-standard technique is employed to precisely determine the exact purity of the MMF, quantify its concentration, and to meticulously identify and quantify any trace impurities or degradation products.
- Nuclear Magnetic Resonance (NMR) Spectroscopy (¹H and ¹³C): Utilized to provide exquisitely detailed information about the molecular structure of MMF, unequivocally confirming its identity and ensuring there are no unintended structural deviations.
- Mass Spectrometry (MS): This powerful analytical tool identifies the precise molecular weight of the compound and is highly effective in detecting even trace-level impurities by meticulously analyzing their mass-to-charge ratio.
- Fourier-Transform Infrared (FTIR) Spectroscopy: FTIR provides a unique “fingerprint” of the compound, identifying the functional groups present and further confirming its chemical structure and overall purity.
- Elemental Analysis (EA): Determines the elemental composition (C, H, O) of the sample, which is then compared against the theoretical composition of MMF, providing an additional layer of purity verification.
- Residual Solvents Analysis (GC-MS): Ensures that no harmful residual solvents from the synthesis or manufacturing process are present in the API.
The stringent application of these advanced, multi-modal analytical techniques guarantees that our MET Fumarate delivers the consistent, high-grade purity essential for reproducible research. This superior quality directly translates to robust and reliable experimental outcomes, empowering researchers to draw accurate and defensible conclusions, thereby accelerating their scientific discoveries without any concerns about unexpected variables introduced by lesser-quality reagents.
Safety & Handling Guidelines
MET Fumarate (Monomethyl Fumarate) is strictly for research purposes only and is not intended for human consumption, animal consumption, medical use, diagnostic procedures, or therapeutic applications of any kind whatsoever. While Monomethyl Fumarate is an active metabolite of an FDA-approved drug (Dimethyl Fumarate), this product is sold as a research chemical and is not for direct administration to humans or animals. Its handling requires strict adherence to laboratory safety protocols. GHS classifications indicate it can cause serious eye damage, skin irritation, and may cause an allergic skin reaction or respiratory irritation. High doses are potentially nephrotoxic with long-term exposure.
- Always wear appropriate personal protective equipment (PPE), including, but not limited to, a laboratory coat, chemical splash goggles or safety glasses, and chemical-resistant gloves (e.g., nitrile) when handling the product. Avoid direct skin contact and ingestion.
- Work exclusively in a well-ventilated area or, ideally, under a certified chemical fume hood to minimize any potential exposure to airborne powder.
- Avoid any direct contact with skin, eyes, and clothing. In the event of accidental contact, rinse the affected area thoroughly with copious amounts of water for at least 15 minutes and seek immediate medical attention if irritation or symptoms persist.
- Store the product securely in its original, tightly sealed, light-blocking packaging, in a cool, dark, and very dry environment (ideally -20°C freezer for long-term stability), far removed from incompatible materials, unauthorized personnel, and any direct sources of sunlight or heat.
- Dispose of the product and any contaminated materials strictly according to all applicable local, regional, and national regulations for hazardous chemical waste.
- Always consult the comprehensive Safety Data Sheet (SDS) for Monomethyl Fumarate for detailed hazard information, safe handling procedures, first-aid measures, and emergency protocols before any use.
Global Shipping & Discreet Delivery
We recognize that the secure and confidential procurement of research chemicals is as critically important as their intrinsic purity. Our robust global shipping infrastructure is meticulously designed to provide unparalleled service to the international scientific community, with an unwavering commitment to your absolute privacy and the secure, timely delivery of your order. When you choose to buy MET Fumarate online from us, you benefit from a meticulously planned and executed delivery process:
- Worldwide Reach: We offer expedited and highly reliable shipping services to virtually every country across the globe, ensuring that researchers on all continents have seamless access to our high-quality products.
- Discreet Packaging: All orders are meticulously shipped in completely plain, nondescript packaging. There are absolutely no company logos, product names, or any other identifying marks whatsoever on the exterior of the parcel that would, in any way, indicate its sensitive contents.
- Secure Contents: The powder is contained within a sealed, durable, and light-blocking container, which is then securely packed to prevent any damage or tampering during transit.
- No Chemical Names on Parcel: For maximum security and unparalleled privacy, the shipping labels will never contain the precise chemical name of the product. Instead, generic descriptions (e.g., “scientific sample,” “laboratory material”) or non-descriptive codes are utilized to comply with international customs regulations without compromising your anonymity or the confidential nature of your purchase.
- Reliable Tracking: The vast majority of our international orders are dispatched with comprehensive tracking information, allowing you to closely monitor your shipment’s progress from the moment of dispatch right through to successful delivery, providing complete peace of mind.
- Efficient Logistics: Our strategic partnerships with leading global couriers and freight forwarders ensure that your order is processed with exceptional speed and efficiency, minimizing transit times and getting your invaluable research materials to your laboratory as swiftly as humanly possible.
We take immense pride in our ability to consistently offer truly stealth packaging that unequivocally prioritizes your confidentiality, establishing us as the preferred and trusted choice for research chemicals where discretion is of paramount importance.
Why Choose Us?
Selecting the right supplier for your critical research chemicals is a monumental decision that directly influences the validity, efficiency, and safety of your scientific endeavors. Here’s why scientists and research institutions across the globe implicitly trust us as their premier source for MET Fumarate:
- Uncompromising Purity: Our steadfast commitment to consistently deliver ≥98% product purity, meticulously verified by extensive third-party testing, ensures reliable, reproducible, and impactful research outcomes.
- Pharmaceutical Relevance: As an active metabolite of an approved drug, our MET Fumarate is invaluable for studies requiring high relevance to clinical applications and drug discovery.
- Dedicated Customer Support: Our team of highly knowledgeable, professional, and responsive customer support specialists is readily available to assist you with any inquiries, ranging from detailed product specifications to precise order tracking, ensuring a flawlessly seamless and positive purchasing experience.
- Fast & Reliable Shipping: We prioritize exceptionally rapid order processing and dispatch, synergistically coupled with highly efficient and robust global shipping services, to guarantee that your invaluable research materials reach your facility promptly, wherever you are situated in the world.
- Ultimate Stealth Packaging: We possess a profound understanding of the critical importance of discretion. Our packaging is meticulously engineered to be utterly plain, entirely unmarked, and securely contained, thereby guaranteeing absolute and complete confidentiality for your research needs.
- Trusted Global Reputation: Years of dedicated, ethical, and consistent service to the global scientific community have unequivocally cemented our reputation as a highly reliable, transparent, and trusted supplier of the highest quality research chemicals.
- Competitive Pricing: We are committed to offering premium quality products at highly competitive price points, thereby providing exceptional value for your critical research budget without ever compromising on our stringent purity standards or our superior service.
- Secure Payment Options: We provide a diverse range of robust and secure payment methods to ensure that all your transactions are processed safely, efficiently, and with the utmost protection of your financial information.
When you choose to buy MET Fumarate from us, you are not merely acquiring a chemical compound; you are making a strategic investment in a partnership that unequivocally supports your ambitious scientific objectives with integrity, unwavering reliability, and unparalleled service.
Legal & Safety Disclaimer
MET Fumarate (Monomethyl Fumarate) is sold strictly and exclusively for legitimate scientific research and bona fide laboratory use only. The contents of this product are NOT FOR HUMAN CONSUMPTION, ANIMAL CONSUMPTION, MEDICAL USE, DIAGNOSTIC PROCEDURES, OR THERAPEUTIC PURPOSES OF ANY KIND WHATSOEVER.
- Research Use Only: This product is intended solely for in vitro and, where ethically approved, in vivo (non-human) research applications to be conducted exclusively by qualified, experienced, and competent professionals operating within strictly controlled laboratory environments.
- Age Restriction: By proceeding with the purchase of this product, the buyer explicitly confirms and warrants that they are at least eighteen (18) years of age.
- Legal Compliance (Douala, Littoral Region, Cameroon & International): The buyer assumes complete and absolute responsibility for comprehensively understanding and meticulously complying with all applicable local, regional, and national laws, statutes, and regulations pertaining to the purchase, possession, and use of this specific research chemical. Monomethyl Fumarate (MMF) is the active metabolite of Dimethyl Fumarate (DMF), an FDA-approved drug (e.g., Tecfidera, Vumerity) for multiple sclerosis. As such, it is not a “recreational” or “designer drug” but a compound with significant pharmaceutical relevance. Its regulatory status in Cameroon would likely fall under regulations governing active pharmaceutical ingredients (APIs), drug precursors, or substances related to approved medications. As of Thursday, June 19, 2025, in Douala, Littoral Region, Cameroon, while MMF may not be explicitly listed as a controlled illicit substance, its pharmaceutical relevance means its import, possession, and use for anything other than legitimate, licensed research would likely be strictly controlled or prohibited. Buyers are strongly advised to consult relevant national drug and pharmaceutical laws, and customs regulations in Cameroon to ensure full compliance. We shall not be held liable or responsible for any legal repercussions, penalties, or damages arising from the misuse, illegal possession, or unlawful distribution of this product.
- Risk Assumption (PHARMACEUTICAL RESEARCH REAGENT): The buyer explicitly acknowledges and accepts the inherent and significant risks unequivocally associated with the handling and experimentation of research chemicals, particularly those with known pharmacological activity. While Monomethyl Fumarate is part of an approved therapeutic regimen, this product is sold as a research reagent and its direct human consumption or non-research animal administration is strictly prohibited and potentially harmful. GHS classifications indicate it can cause serious eye damage, skin irritation, and may cause an allergic skin reaction or respiratory irritation. The buyer further agrees to diligently undertake all necessary and appropriate precautions, including, but not limited to, the consistent use of proper personal protective equipment (PPE) and strict adherence to established standard laboratory safety procedures and best practices, treating this substance as potentially hazardous.
- No Medical Claims: No claims, express or implied, are made or intended regarding the medical, therapeutic, recreational, or any other non-research-related uses of this product. Any such use is strictly and absolutely prohibited and is entirely contrary to the explicitly stated and intended purpose of this product.
- Waiver of Liability: By completing the purchase, the buyer irrevocably agrees to release, indemnify, defend, and hold harmless the supplier from any and all claims, demands, liabilities, actions, causes of action, or damages (including reasonable legal fees) whatsoever, arising directly or indirectly from the proper use, misuse, or illegal possession of the product.
This disclaimer serves as a critical and unambiguous reminder of the specific, limited, and legally defined scope of the product’s intended use and the comprehensive legal responsibilities incumbent upon the purchaser.
FAQ Section
Here are some frequently asked questions about MET Fumarate (Monomethyl Fumarate):
Q1: What is MET Fumarate (Monomethyl Fumarate) used for in research?
A1: MET Fumarate (MMF) is used for advanced scientific and pharmacological research as it is the active metabolite of Dimethyl Fumarate (DMF), an approved drug for MS and psoriasis. Researchers study its immunomodulatory, anti-inflammatory, and antioxidant properties, its role in activating the Nrf2 pathway and GPR109A, and its potential in neurological disease models, in in vitro and in vivo (non-human) studies.
Q2: Is MET Fumarate legal for research?
A2: The legal status of Monomethyl Fumarate for research varies. As an active metabolite of an approved pharmaceutical drug, its import and use for legitimate scientific research generally fall under pharmaceutical regulations, which are strict. In Cameroon, as elsewhere, it is not for human consumption or recreational use and its handling for research would require compliance with all relevant drug and research substance regulations. Researchers must independently verify its legal status for their specific research use in their jurisdiction.
Q3: How discreet is shipping for MET Fumarate?
A3: We use highly discreet packaging for all orders of MET Fumarate. This means plain, unmarked envelopes or boxes with no company logos, product names, or identifying marks on the exterior. Generic descriptions are used for customs purposes to ensure your privacy and secure delivery.
Q4: What is the purity of your MET Fumarate, and how is it verified?
A4: Our MET Fumarate has a purity of ≥98%. This purity is rigorously verified through multiple analytical techniques, including HPLC, NMR, and Mass Spectrometry, conducted by independent, accredited laboratories.
Q5: What are the safety precautions for handling MET Fumarate?
A5: MET Fumarate should be handled with caution. Always wear appropriate PPE (lab coat, gloves, eye protection), work in a fume hood to prevent inhalation of powder, and avoid all direct contact or ingestion. It can cause serious eye damage and skin irritation. MET Fumarate is not for human consumption. Refer to the product’s Safety Data Sheet (SDS) for detailed safety information.
